A recent study, including Cluster Doctoral Researcher Alexander Berkes, Alumnus Pascal Kiefer and PI Martin Wegener, explores how the geometry of carrier particles affects drug delivery in dry powder inhalers. The team used multi-photon 3D laser printing to create millions of microparticles with different shapes and surface textures. The spiked Pharmacone design performed best, enabling the highest fraction of respirable drug particles. Although these particles are not intended for inhalation, this approach suggests the possibility of future biocompatible, precision-engineered carriers for more effective lung therapies.
© Wostry et al., Communications Materials 2025, CC BY 4.0