With six million euros in funding from the Carl-Zeiss-Stiftung, researchers at the Heidelberg University are developing innovative approaches for the engineering of complex organoid models. The interdisciplinary project, which includes Principal Investigators Christine Selhuber-Unkel, Wolfram Pernice, Joachim Wittbordt, Michael Boutros and Peer Fischer, aims to create advanced organ-on-a-chip systems for studying multi-organ interactions, enabling precise disease modeling and novel therapeutic testing while reducing animal testing.