Bridging Top-Down and Bottom-Up Approaches in Synthetic Biology

In a new paper published in Nature Communications, a group of researchers including Cluster Young Scientist Kevin Jahnke and Principal Investigators Rasmus R. Schröder, Joachim Spatz and Kerstin Göpfrich demonstrate that the use of top-down engineered bacteria can enhance bottom-up assembled synthetic cells, thus providing a vision to bridge the gap between the two approaches in synthetic biology.