Organoids for Medical Applications (C2.3)

Tissues and organs are comprised of multiple cell types that assemble as building blocks into distinct patterns. In project C2.3, we will integrate a variety of new methods and approaches to address the various challenges that arise when using organoids as a model system. We will combine new bioassembly manufacturing methods with parallelized 3D printing and robotic screening platforms to form larger 3D assembloids on the mm-to-cm scale, mimicking the complexity of in vivo organs. These will be useful for, for example, testing drug-induced responses of intestinal organoids and recording electrical activity from brain disease models.